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Grade 12 · CAPS · NSC 2026

Grade 12 Life Sciences (CAPS) – topics, exam weighting and study time

The 14 matric Life Sciences topics in the portal, grouped by NSC exam paper, with the typical mark weighting, the study sections in each topic, the number of exam-style questions and how long each topic takes to study.

Topics
14
Study sections
60
Exam-style questions
125
Total study time
≈ 57 h 25 min

Open a topic for what it covers, how it is examined and a daily study target. See the matric exam timetable 2026. In Grade 10 or 11? See the Grade 10 and Grade 11 Life Sciences topics.

Life Sciences · Paper 1

Paper 1 topics

Fri 13 Nov 2026 · 09:002½ hours · 150 marks8 topics · ≈ 29 h 00 min

Reproduction in Vertebrates

Reproduction in vertebrates ≈ 8/150 in Paper 1 (5%, DBE Examination Guidelines 2021)
Sections 3Exam questions 8 (58 marks)Study time ≈ 2 h 30 minnotes 1 h 10 · exam questions 1 h 10
Show the 3 sections
  1. Fertilisation and where the embryo develops25 min
  2. The amniotic egg20 min
  3. Precocial and altricial development; parental care25 min

Notes and worked examples 1 h 10 min · 8 exam-style questions (58 marks) at exam pace 1 h 10 min · quiz 10 min

Human Reproduction

Human reproduction ≈ 41/150 in Paper 1 (27%, DBE Examination Guidelines 2021)
Sections 5Exam questions 10 (95 marks)Study time ≈ 5 h 00 minnotes 2 h 55 · exam questions 1 h 55
Show the 5 sections
  1. The male and female reproductive systems; puberty35 min
  2. Gametogenesis and the structure of the gametes35 min
  3. The menstrual cycle and its hormones45 min
  4. Fertilisation, implantation and early development30 min
  5. The placenta, the membranes and the foetus30 min

Notes and worked examples 2 h 55 min · 10 exam-style questions (95 marks) at exam pace 1 h 55 min · quiz 10 min

Responding to the Environment: the Nervous System

Responding to the environment (humans: nervous system, eye, ear) ≈ 54/150 in Paper 1 (36%, DBE Examination Guidelines 2021)
Sections 4Exam questions 9 (87 marks)Study time ≈ 3 h 55 minnotes 2 h 00 · exam questions 1 h 45
Show the 4 sections
  1. Organisation of the nervous system: CNS, PNS and ANS25 min
  2. The brain and spinal cord; Alzheimer's disease35 min
  3. Neurons and synapses; multiple sclerosis30 min
  4. The reflex arc and reflex action30 min

Notes and worked examples 2 h 00 min · 9 exam-style questions (87 marks) at exam pace 1 h 45 min · quiz 10 min

Responding to the Environment: the Human Eye

Part of Responding to the environment (humans) ≈ 54/150 in Paper 1 (36%, shared with the nervous system and the ear)
Sections 4Exam questions 8 (80 marks)Study time ≈ 3 h 45 minnotes 2 h 00 · exam questions 1 h 35
Show the 4 sections
  1. Structure of the eye and the functions of its parts40 min
  2. Accommodation and binocular vision30 min
  3. The pupillary mechanism20 min
  4. Visual defects: short- and long-sightedness, astigmatism and cataracts30 min

Notes and worked examples 2 h 00 min · 8 exam-style questions (80 marks) at exam pace 1 h 35 min · quiz 10 min

Responding to the Environment: the Human Ear

Part of Responding to the environment (humans) ≈ 54/150 in Paper 1 (36%, shared with the nervous system and the eye)
Sections 4Exam questions 8 (77 marks)Study time ≈ 3 h 25 minnotes 1 h 45 · exam questions 1 h 30
Show the 4 sections
  1. Structure of the ear and the functions of its parts35 min
  2. Hearing25 min
  3. Balance: the role of the maculae and cristae25 min
  4. Hearing problems: middle-ear infection and deafness20 min

Notes and worked examples 1 h 45 min · 8 exam-style questions (77 marks) at exam pace 1 h 30 min · quiz 10 min

The Human Endocrine System

Endocrine system and homeostasis ≈ 34/150 in Paper 1 (23%, DBE Examination Guidelines 2021)
Sections 3Exam questions 8 (61 marks)Study time ≈ 2 h 55 minnotes 1 h 30 · exam questions 1 h 15
Show the 3 sections
  1. Endocrine glands and their hormones40 min
  2. Endocrine vs nervous system; adrenalin25 min
  3. Negative feedback: thyroxin, TSH and goitre25 min

Notes and worked examples 1 h 30 min · 8 exam-style questions (61 marks) at exam pace 1 h 15 min · quiz 10 min

Homeostasis in Humans

Endocrine system and homeostasis ≈ 34/150 in Paper 1 (23%, DBE Examination Guidelines 2021)
Sections 4Exam questions 9 (85 marks)Study time ≈ 3 h 55 minnotes 2 h 05 · exam questions 1 h 40
Show the 4 sections
  1. Homeostasis, negative feedback and blood glucose; diabetes mellitus40 min
  2. Water and salt balance: ADH and aldosterone35 min
  3. Regulation of the carbon dioxide level20 min
  4. Thermoregulation30 min

Notes and worked examples 2 h 05 min · 9 exam-style questions (85 marks) at exam pace 1 h 40 min · quiz 10 min

Responding to the Environment: Plants

Responding to the environment (plants) ≈ 13/150 in Paper 1 (9%, DBE Examination Guidelines 2021)
Sections 4Exam questions 9 (82 marks)Study time ≈ 3 h 35 minnotes 1 h 45 · exam questions 1 h 40
Show the 4 sections
  1. Plant hormones: auxins, gibberellins and abscisic acid25 min
  2. Phototropism and geotropism: the role of auxins30 min
  3. Investigating tropisms35 min
  4. Plant defence mechanisms15 min

Notes and worked examples 1 h 45 min · 9 exam-style questions (82 marks) at exam pace 1 h 40 min · quiz 10 min

Paper 1 total8 topics · 31 sections · 69 questions · ≈ 29 h 00 min

Life Sciences · Paper 2

Paper 2 topics

Mon 16 Nov 2026 · 09:002½ hours · 150 marks6 topics · ≈ 28 h 25 min

DNA: The Code of Life

DNA: the code of life ≈ 27/150 marks in Paper 2 (18%)
Sections 5Exam questions 9 (113 marks)Study time ≈ 4 h 40 minnotes 2 h 15 · exam questions 2 h 15
Show the 5 sections
  1. Nucleic acids, the structure and location of DNA30 min
  2. DNA replication25 min
  3. DNA profiling and its uses25 min
  4. RNA and transcription25 min
  5. Translation and using codon tables30 min

Notes and worked examples 2 h 15 min · 9 exam-style questions (113 marks) at exam pace 2 h 15 min · quiz 10 min

Meiosis

Meiosis ≈ 21/150 marks in Paper 2 (14%)
Sections 5Exam questions 9 (108 marks)Study time ≈ 4 h 40 minnotes 2 h 20 · exam questions 2 h 10
Show the 5 sections
  1. Chromosomes, haploid and diploid cells, and where meiosis happens25 min
  2. Interphase and meiosis I35 min
  3. Meiosis II25 min
  4. Crossing over, random arrangement and the importance of meiosis25 min
  5. Abnormal meiosis (non-disjunction, Down syndrome) and mitosis vs meiosis30 min

Notes and worked examples 2 h 20 min · 9 exam-style questions (108 marks) at exam pace 2 h 10 min · quiz 10 min

Genetics and Inheritance 1: Monohybrid Crosses, Blood Groups and Sex-linked Inheritance

Genetics and inheritance ≈ 48/150 marks in Paper 2 (32%), shared with Genetics 2 (dihybrid crosses, pedigrees, mutations, biotechnology)
Sections 5Exam questions 9 (100 marks)Study time ≈ 4 h 35 minnotes 2 h 25 · exam questions 2 h 00
Show the 5 sections
  1. Concepts in inheritance25 min
  2. Monohybrid crosses (complete dominance)35 min
  3. Incomplete dominance and co-dominance25 min
  4. Multiple alleles: the ABO blood groups25 min
  5. Sex determination and sex-linked inheritance35 min

Notes and worked examples 2 h 25 min · 9 exam-style questions (100 marks) at exam pace 2 h 00 min · quiz 10 min

Genetics and Inheritance 2: Dihybrid Crosses, Pedigrees, Mutations and Biotechnology

Genetics and inheritance ≈ 48/150 marks in Paper 2 (32%), shared with Genetics 1 (monohybrid crosses, blood groups, sex-linked inheritance)
Sections 5Exam questions 10 (111 marks)Study time ≈ 5 h 00 minnotes 2 h 35 · exam questions 2 h 15
Show the 5 sections
  1. Dihybrid crosses40 min
  2. Pedigree diagrams (genetic lineages)30 min
  3. Mutations30 min
  4. Genetic engineering, stem cells and cloning35 min
  5. Paternity testing and genetic links (mitochondrial DNA)20 min

Notes and worked examples 2 h 35 min · 10 exam-style questions (111 marks) at exam pace 2 h 15 min · quiz 10 min

Evolution by Natural Selection

Evolution ≈ 54/150 marks in Paper 2 (36%), shared with Human evolution
Sections 5Exam questions 10 (127 marks)Study time ≈ 5 h 10 minnotes 2 h 30 · exam questions 2 h 30
Show the 5 sections
  1. Evolution as a theory, and the evidence for evolution30 min
  2. Variation – the raw material for evolution25 min
  3. Lamarck, Darwin and punctuated equilibrium35 min
  4. Artificial selection, speciation and reproductive isolation35 min
  5. Evolution in present times: resistance25 min

Notes and worked examples 2 h 30 min · 10 exam-style questions (127 marks) at exam pace 2 h 30 min · quiz 10 min

Human Evolution

Evolution ≈ 54/150 marks in Paper 2 (36%), shared with Evolution by natural selection
Sections 4Exam questions 9 (107 marks)Study time ≈ 4 h 20 minnotes 2 h 00 · exam questions 2 h 10
Show the 4 sections
  1. Humans as primates: phylogeny and shared characteristics25 min
  2. Humans compared with African apes: skull, teeth and bipedalism35 min
  3. Fossil evidence: Ardipithecus, Australopithecus and Homo35 min
  4. Out of Africa: fossils, mitochondrial DNA and tools25 min

Notes and worked examples 2 h 00 min · 9 exam-style questions (107 marks) at exam pace 2 h 10 min · quiz 10 min

Paper 2 total6 topics · 29 sections · 56 questions · ≈ 28 h 25 min

How the study time is estimated

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